Download Chemical Biology of Nucleic Acids: Fundamentals and Clinical by Volker A. Erdmann,Wojciech T. Markiewicz,Jan Barciszewski PDF

By Volker A. Erdmann,Wojciech T. Markiewicz,Jan Barciszewski

This quantity comprises 29 engrossing chapters contributed by means of world wide, top learn teams within the box of chemical biology. themes contain pre-biology; the institution of the genetic code; isomerization of RNA; harm of nucleobases in RNA; the dynamic constitution of nucleic acids and their analogs in DNA replication, additional- and intra-cellular delivery; molecular crowding by way of ionic beverages; new applied sciences allowing the amendment of gene expression through enhancing of healing genes; using riboswitches; the amendment of mRNA cap areas; new techniques to become aware of properly transformed RNAs with EPR spectroscopy and using parallel and high-throughput options for the research of the constitution and new capabilities of nucleic acids. This quantity discusses how chemistry can upload new frontiers to the sector of nucleic acids in molecular medication, biotechnology and nanotechnology and isn't in basic terms a useful resource of data to chemists, biochemists and existence scientists yet also will stimulate destiny research.

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